BIOMOLMACS Innovative Training Network (Project 859416)
100% / offered starting date is 01/06/2020
You are invited to apply for a 36-month position of Early-Stage Researcher (ESR) at the Department of Chemistry, University of Basel, as part of the Horizon 2020 Marie Skłodowska-Curie Innovative Training Network (ITN) BIOMOLMACS. Details about this training programme and further information on the consortium are provided on www.biomolmacs.com webpage.
The successful applicant will work on Artificial organelles in cells (ESR12), a research area combining polymer chemistry, pharmaceutics and biomedical science. This ESR12 position is offered in conjunction with a PhD studentship at the University of Basel, subject to the applicant satisfying the admissions requirements of the university. The ESR candidate can be enrolled on a 4-year structured PhD, but she/he should be required to self-fund after the initial 36 months for the successful completion of the PhD program.
More information on the research interests of Prof. Wolfgang Meier can be found on his website: https://www.chemie1.unibas.ch/~meier/.
The ESR12, who will be appointed on this project, will focus on the development of molecular factories for in-vivo drug production and release. An efficient and selective encapsulation of active nanoreactors is the basis for locally producing specific drugs. The selective encapsulation of nanoreactors in a larger compartment is based on newly synthesized, biodegradable, amphiphilic block copolymers. The kinetics of the reaction cascade in the nanoreactors has to be quantified in solution, in-situ and in-vivo. This requires combination of several sensitive methods like dynamic spectroscopy, fluorescence correlation spectroscopy etc.
Candidates should have or expect to attain a Master degree or equivalent in Chemistry, Materials Science, Biomedical Science, Polymer Chemistry, Pharmaceutics or a related discipline. A research project should have been carried out in at least one of the above disciplines. A demonstrated knowledge of at least three of the following: pharmaceutical formulation development, drug delivery, cell culture/molecular biology, nanotechnology, polymerization techniques is required to carry out the project successfully.
Applicants can be of any nationality, but must not have resided or carried out their main activity (work, studies, etc.) in Switzerland for more than 12 months in the 3 years immediately prior to starting their PhD position. Candidates must be at the time of recruitment in the first four years (full-time equivalent) of their research careers and have not yet been awarded a doctoral degree. This is measured from the date when they obtained the Master's degree.
Interested candidates must be proficient in written and spoken English and able to work in an interdisciplinary team.
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